X-ray diffraction
2.75Å resolution

Crystal structure of Smad2 without exon -MH1 bound to the CAGAC site.

Source organism: Homo sapiens
Entry authors: Kaczmarska Z, Marquez JA, Macias MJ

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Mothers against decapentaplegic homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 139 amino acids
Theoretical weight: 15.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: B7Z5N5 (Residues: 10-143; Coverage: 31%)
Gene name: SMAD2
Sequence domains: MH1 domain
Molecule details ›
Chains: C, D
Length: 18 nucleotides
Theoretical weight: 5.52 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P43212
Unit cell:
a: 80.14Å b: 80.14Å c: 143.84Å
α: 90° β: 90° γ: 90°
R R work R free
0.202 0.201 0.222
Expression systems:
  • Escherichia coli
  • Not provided