6gl8

X-ray diffraction
1.4Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apoptosis regulator Bcl-2; Bcl-2-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 172 amino acids
Theoretical weight: 20.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P10415 (Residues: 9-33, 66-98, 103-206; Coverage: 57%)
  • Canonical: Q07817 (Residues: 28-44, 92-95; Coverage: 9%)
Gene names: BCL2, BCL2L, BCL2L1, BCLX
Sequence domains: Apoptosis regulator proteins, Bcl-2 family

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P212121
Unit cell:
a: 35.09Å b: 46.9Å c: 85.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.178 0.194
Expression system: Escherichia coli BL21(DE3)