PDBe 6gbm

Solution NMR

Solution structure of FUS-RRM bound to stem-loop RNA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
RNA-binding protein FUS Chain: B
Molecule details ›
Chain: B
Length: 102 amino acids
Theoretical weight: 11.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P35637 (Residues: 280-377; Coverage: 19%)
Gene names: FUS, TLS
Sequence domains: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RNA (5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*AP*CP*AP*AP*UP*UP*CP*UP*AP*UP*UP*UP*GP*CP*C)-3') Chain: A
Molecule details ›
Chain: A
Length: 23 nucleotides
Theoretical weight: 7.29 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing
Chemical shifts: BMR34259  
Expression systems:
  • Escherichia coli
  • Not provided