PDBe 6g39

X-ray diffraction
1.45Å resolution

Crystal structure of haspin F605Y mutant in complex with 5-iodotubercidin

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase haspin Chain: A
Molecule details ›
Chain: A
Length: 357 amino acids
Theoretical weight: 40.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: NEW Q8TF76 (Residues: 465-798; Coverage: 42%)
Gene names: GSG2, HASPIN

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P212121
Unit cell:
a: 78.82Å b: 78.99Å c: 79.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.159 0.158 0.175
Expression system: Escherichia coli BL21(DE3)