PDBe 6etv

X-ray diffraction
1.18Å resolution

Crystal structure of KDM4D with tetrazolhydrazide compound 2

Released:
Source organism: Homo sapiens
Entry authors: Malecki PH, Link A, Weiss MS, Heinemann U

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysine-specific demethylase 4D Chain: A
Molecule details ›
Chain: A
Length: 342 amino acids
Theoretical weight: 39.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6B0I6 (Residues: 1-342; Coverage: 65%)
Gene names: JHDM3D, JMJD2D, KDM4D
Sequence domains:

Ligands and Environments

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P43212
Unit cell:
a: 71.49Å b: 71.49Å c: 150.444Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.122 0.121 0.15
Expression system: Escherichia coli BL21(DE3)