PDBe 6ets

X-ray diffraction
1.33Å resolution

Crystal structure of KDM4D with tetrazolhydrazide compound 1

Released:
Source organism: Homo sapiens
Entry authors: Malecki PH, Link A, Weiss MS, Heinemann U

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysine-specific demethylase 4D Chain: A
Molecule details ›
Chain: A
Length: 341 amino acids
Theoretical weight: 39.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6B0I6 (Residues: 1-341; Coverage: 65%)
Gene names: JHDM3D, JMJD2D, KDM4D
Sequence domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.3
Spacegroup: P43212
Unit cell:
a: 71.631Å b: 71.631Å c: 150.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.129 0.129 0.156
Expression system: Escherichia coli BL21(DE3)