PDBe 6eiy

X-ray diffraction
2.15Å resolution

Crystal structure of KDM5B in complex with KDOPZ000034a.

Released:
Source organism: Homo sapiens
Entry authors: Srikannathasan V, Newman JA, Szykowska A, Wright M, Ruda GF, Vazquez-Rodriguez SA, Kupinska K, Strain-Damerell C, Burgess-Brown NA, Arrowsmith CH, Edwards A, Bountra C, Oppermann U, Huber K, von Delft F

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysine-specific demethylase 5B Chain: A
Molecule details ›
Chain: A
Length: 461 amino acids
Theoretical weight: 53.15 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9UGL1 (Residues: 26-100, 374-754; Coverage: 30%)
  • Best match: Q9UGL1-2 (Residues: 377-380, 381-405, 410-790)
Gene names: JARID1B, KDM5B, PLU1, RBBP2H1
Sequence domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P6522
Unit cell:
a: 142.38Å b: 142.38Å c: 152.17Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.188 0.186 0.215
Expression system: Spodoptera frugiperda