PDBe 6eih

X-ray diffraction
2.7Å resolution

The crystal structure of 14-3-3 epsilon in complex with the phosphorylated NELFE peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein epsilon Chain: A
Molecule details ›
Chain: A
Length: 230 amino acids
Theoretical weight: 26.37 KDa
Source organism: Homo sapiens
Expression system: unidentified plasmid
UniProt:
  • Canonical: P62258 (Residues: 3-232; Coverage: 90%)
Gene name: YWHAE
Sequence domains: 14-3-3 protein
SER-ILE-SEP-ARG Chain: P
Molecule details ›
Chain: P
Length: 4 amino acids
Theoretical weight: 543 Da
Source organism: Homo sapiens
Expression system: synthetic construct

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup: C2221
Unit cell:
a: 79.29Å b: 81.186Å c: 81.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.172 0.241
Expression systems:
  • unidentified plasmid
  • synthetic construct