PDBe 6dm1

Electron Microscopy
4.2Å resolution

Open state GluA2 in complex with STZ and blocked by NASPM, after micelle signal subtraction

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor 2; Voltage-dependent calcium channel gamma-2 subunit Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 1031 amino acids
Theoretical weight: 115.18 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
  • Canonical: Q9Y698 (Residues: 2-205, 206-208; Coverage: 64%)
  • Canonical: P19491 (Residues: 25-847; Coverage: 95%)
  • nullnull
Gene names: CACNG2, Glur2, Gria2
Sequence domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.2Å
Relevant EMDB volumes: EMD-7961
Expression system: Homo sapiens