› 6dg1

Solution NMR

NMR structure of the second qRRM2 domain of human hnRNP H

Released:
DOI: 10.2210/pdb6dg1/pdb
PDB entry 6dg1 coloured by chain, ensemble of 10 models, front view.
PDB entry 6dg1 coloured by chain, ensemble of 10 models, side view.
PDB entry 6dg1 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Differential Conformational Dynamics Encoded by the Linker between Quasi RNA Recognition Motifs of Heterogeneous Nuclear Ribonucleoprotein H.
Penumutchu SR, Chiu LY, Meagher JL, Hansen AL, Stuckey JA, Tolbert BS
J Am Chem Soc 140 11661-11673 (2018)
PMID: 30122033

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157318 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 11.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P55795 (Residues: 94-194; Coverage: 23%)
Gene names: FTP3, HNRNPH2, HNRPH2
Sequence domains: RNA recognition motif

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 75%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Heterogeneous Nuclear Ribonucleoproteins Involved in the Functioning of Telomeres in Malignant Cells.
Shishkin et al. (2019)
2 more