PDBe 6cyr

X-ray diffraction
2.2Å resolution

Crystal structure of the UBE2A variant Q93E

Released:

Function and Biology Details

Reaction catalysed:
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin-conjugating enzyme E2 A Chain: A
Molecule details ›
Chain: A
Length: 155 amino acids
Theoretical weight: 17.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P49459 (Residues: 1-152; Coverage: 100%)
Gene names: RAD6A, UBE2A
Sequence domains: Ubiquitin-conjugating enzyme

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE W01B-MX2
Spacegroup: P212121
Unit cell:
a: 37.511Å b: 52.419Å c: 88.59Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.204 0.249
Expression system: Escherichia coli