6cs2

Electron Microscopy
4.4Å resolution

SARS Spike Glycoprotein - human ACE2 complex, Stabilized variant, all ACE2-bound particles

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fibritin; Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1215 amino acids
Theoretical weight: 134.74 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
  • Canonical: P10104 (Residues: 458-484; Coverage: 6%)
  • Canonical: P59594 (Residues: 14-1190; Coverage: 95%)
Gene names: 2, S, wac
Sequence domains:
Processed angiotensin-converting enzyme 2 Chain: D
Molecule details ›
Chain: D
Length: 605 amino acids
Theoretical weight: 70.03 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9BYF1 (Residues: 19-615; Coverage: 76%)
  • Best match: Q9BYF1-2 (Residues: 19-555)
Gene names: ACE2, UNQ868/PRO1885
Sequence domains: Angiotensin-converting enzyme

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.4Å
Relevant EMDB volumes: EMD-7582
Expression system: Homo sapiens