6c6d

X-ray diffraction
5.5Å resolution

20mer crystal structure of CC chemokine 5 (CCL5)

Released:
Source organism: Homo sapiens
Entry authors: Liang WG, Tang WJ

Function and Biology Details

Structure analysis Details

Assembly composition:
homo 20-mer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 5 Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
Length: 65 amino acids
Theoretical weight: 7.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13501 (Residues: 27-91; Coverage: 96%)
Gene names: CCL5, D17S136E, SCYA5
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 119.866Å b: 322.783Å c: 157.512Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.248 0.286
Expression system: Escherichia coli