PDBe 6c09

X-ray diffraction
2.95Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
T-cell surface glycoprotein CD1c Chain: A
Molecule details ›
Chain: A
Length: 287 amino acids
Theoretical weight: 32.28 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P29017 (Residues: 19-297; Coverage: 88%)
Gene name: CD1C
Sequence domains: Immunoglobulin C1-set domain
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 108 amino acids
Theoretical weight: 12.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
3C8 T cell receptor alpha-chain Chain: C
Molecule details ›
Chain: C
Length: 205 amino acids
Theoretical weight: 22.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
3C8 T cell receptor beta-chain Chain: D
Molecule details ›
Chain: D
Length: 247 amino acids
Theoretical weight: 27.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P3121
Unit cell:
a: 173.17Å b: 173.17Å c: 82.47Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.174 0.208
Expression systems:
  • Homo sapiens
  • Escherichia coli BL21