PDBe 6byk

X-ray diffraction
3Å resolution

Structure of 14-3-3 beta/alpha bound to O-ClcNAc peptide


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein beta/alpha Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 230 amino acids
Theoretical weight: 26.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P31946 (Residues: 3-232; Coverage: 94%)
Gene name: YWHAB
Sequence domains: 14-3-3 protein
ATPPVSQASSTT O-GlcNac peptide Chains: G, J, K, R
Molecule details ›
Chains: G, J, K, R
Length: 12 amino acids
Theoretical weight: 1.15 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P21
Unit cell:
a: 82.67Å b: 71.45Å c: 95.759Å
α: 90° β: 111.61° γ: 90°
R R work R free
0.22 0.215 0.268
Expression systems:
  • Escherichia coli
  • Not provided