PDBe 6b72

X-ray diffraction
3.2Å resolution

A novel HIV-1 Nef dimer interface induced by a single octyl-glucoside molecule


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
C-terminal core protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 151 amino acids
Theoretical weight: 17.76 KDa
Source organism: HIV-1 M:B_ARV2/SF2
Expression system: Escherichia coli
  • Canonical: P03407 (Residues: 57-207; Coverage: 72%)
Gene name: nef

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P3221
Unit cell:
a: 109.577Å b: 109.577Å c: 247.04Å
α: 90° β: 90° γ: 120°
R R work R free
0.234 0.233 0.251
Expression system: Escherichia coli