PDBe 6ap0

X-ray diffraction
2.58Å resolution

Crystal structure of human FLASH N-terminal domain C54S/C83A (Crystal form 2)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CASP8-associated protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 96 amino acids
Theoretical weight: 11.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UKL3 (Residues: 51-137; Coverage: 4%)
Gene names: CASP8AP2, FLASH, KIAA1315, RIP25

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: C2
Unit cell:
a: 63.478Å b: 44.346Å c: 68.433Å
α: 90° β: 98.65° γ: 90°
R-values:
R R work R free
0.216 0.214 0.249
Expression system: Escherichia coli