PDBe 6aoz

X-ray diffraction
2.1Å resolution

Crystal structure of human FLASH N-terminal domain C54S/C83A (Crystal form 1)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CASP8-associated protein 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 96 amino acids
Theoretical weight: 11.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UKL3 (Residues: 51-137; Coverage: 4%)
Gene names: CASP8AP2, FLASH, KIAA1315, RIP25

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P1
Unit cell:
a: 39.281Å b: 41.086Å c: 60.951Å
α: 95.58° β: 105.18° γ: 113.4°
R-values:
R R work R free
0.218 0.215 0.254
Expression system: Escherichia coli