PDBe 6a69

Electron Microscopy
4.11Å resolution

Cryo-EM structure of a P-type ATPase

Released:
Source organism: Homo sapiens
Primary publication:
Structure of the human plasma membrane Ca
OpenAccess logo Nat Commun 9 3623 (2018)
PMID: 30190470
Related structures: EMD-6987

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Plasma membrane calcium-transporting ATPase 1 Chain: A
Molecule details ›
Chain: A
Length: 1274 amino acids
Theoretical weight: 140.99 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P20020 (Residues: 1-1117, 1118-1220; Coverage: 100%)
  • Best match: P20020-1 (Residues: 1-1258)
Gene names: ATP2B1, PMCA1
Sequence domains:
Neuroplastin Chain: B
Molecule details ›
Chain: B
Length: 282 amino acids
Theoretical weight: 31.33 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y639 (Residues: 146-398; Coverage: 68%)
  • Best match: Q9Y639-1 (Residues: 1-282)
Gene names: NPTN, SDFR1, SDR1
Sequence domains: Immunoglobulin domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.11Å
Relevant EMDB volumes: EMD-6987
Expression system: Homo sapiens