X-ray diffraction
3.29Å resolution

Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain in complex with mouse nectin-like molecule 1 (mNecl-1) Ig1 domain, 3.3A


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Cell adhesion molecule 4 Chains: A, C
Molecule details ›
Chains: A, C
Length: 299 amino acids
Theoretical weight: 33.3 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
  • Canonical: Q8R464 (Residues: 25-317; Coverage: 80%)
Gene names: Cadm4, Igsf4c, Necl4, Tsll2
Sequence domains:
Cell adhesion molecule 3 Chain: B
Molecule details ›
Chain: B
Length: 147 amino acids
Theoretical weight: 16 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: Q99N28 (Residues: 23-133; Coverage: 30%)
Gene names: Cadm3, Igsf4b, Necl1, Syncam3, Tsll1
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P321
Unit cell:
a: 207.483Å b: 207.483Å c: 52.937Å
α: 90° β: 90° γ: 120°
R R work R free
0.246 0.243 0.302
Expression systems:
  • Trichoplusia ni
  • Escherichia coli