5zf6

X-ray diffraction
2.8Å resolution

Crystal structure of the dimeric human PNPase

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polyribonucleotide nucleotidyltransferase 1, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 647 amino acids
Theoretical weight: 70.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8TCS8 (Residues: 46-669; Coverage: 80%)
Gene names: PNPASE, PNPT1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: P21
Unit cell:
a: 81.335Å b: 109.334Å c: 84.501Å
α: 90° β: 117.41° γ: 90°
R-values:
R R work R free
0.197 0.193 0.249
Expression system: Escherichia coli