5yto

X-ray diffraction
1.9Å resolution

Crystal Structure of human Superoxide Dismutase I (hSOD1) in complex with a napthalene-catechol linked compound.

Released:
Source organism: Homo sapiens
Entry authors: Padmanabhan B, Manjula R

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Cu-Zn] Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 180 amino acids
Theoretical weight: 19.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P00441 (Residues: 1-154; Coverage: 100%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P6322
Unit cell:
a: 243.941Å b: 243.941Å c: 144.775Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.181 0.179 0.215
Expression system: Escherichia coli BL21