› 5ys2

X-ray diffraction
2.7Å resolution

Structure of the domain IV(D_IV) of Pseudorabies virus glycoprotein B( PRV gB)

Released:
DOI: 10.2210/pdb5ys2/pdb
PDB entry 5ys2 coloured by chain, front view.
PDB entry 5ys2 coloured by chain, side view.
PDB entry 5ys2 coloured by chain, top view.
Source organism: Suid alphaherpesvirus 1
Primary publication:
Two classes of protective antibodies against Pseudorabies virus variant glycoprotein B: Implications for vaccine design.
Li X, Yang F, Hu X, Tan F, Qi J, Peng R, Wang M, Chai Y, Hao L, Deng J, Bai C, Wang J, Song H, Tan S, Lu G, Gao GF, Shi Y, Tian K
PLoS Pathog 13 e1006777 (2017)
PMID: 29261802

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycoprotein gB Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 254 amino acids
Theoretical weight: 27.6 KDa
Source organism: Suid alphaherpesvirus 1
Expression system: Trichoplusia ni
UniProt:
  • Canonical: T2FL65 (Residues: 546-700; Coverage: 17%)
Gene names: UL27, UL28, gB
Sequence domains: Herpesvirus Glycoprotein B ectodomain
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Unit cell:
a: 91.911Å b: 119.85Å c: 123.771Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.227 0.291
Expression system: Trichoplusia ni

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Citations

3 review citations

The structural basis of herpesvirus entry.
Connolly et al. (2021)
2 more