5ypo

X-ray diffraction
2.29Å resolution

Crystal structure of PSD-95 GK domain in complex with phospho-SAPAP peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Disks large homolog 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 189 amino acids
Theoretical weight: 21.69 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P31016 (Residues: 531-713; Coverage: 25%)
Gene names: Dlg4, Dlgh4, Psd95
Sequence domains: Guanylate kinase
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Disks large-associated protein 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 15 amino acids
Theoretical weight: 1.77 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O14490 (Residues: 370-384; Coverage: 2%)
Gene names: DAP1, DLGAP1, GKAP

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P212121
Unit cell:
a: 33.776Å b: 84.063Å c: 165.123Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.179 0.226
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided