X-ray diffraction
1.52Å resolution

Crystal structure of the GluA2o LBD in complex with glutamate and LY451395

Source organism: Homo sapiens
Entry authors: Sogabe S, Igaki S, Hirokawa A, Zama Y, Lane W, Snell G

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Glutamate receptor 2 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 263 amino acids
Theoretical weight: 29.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P42262 (Residues: 413-527, 653-796; Coverage: 30%)
Gene names: GLUR2, GRIA2
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: P21
Unit cell:
a: 113.724Å b: 161.913Å c: 46.964Å
α: 90° β: 89.97° γ: 90°
R R work R free
0.204 0.202 0.233
Expression system: Escherichia coli