› 5ybd

X-ray diffraction
2.77Å resolution

X-ray structure of ETS domain of Ergp55 in complex with E74DNA

Released:
DOI: 10.2210/pdb5ybd/pdb
PDB entry 5ybd coloured by chain, front view.
PDB entry 5ybd coloured by chain, side view.
PDB entry 5ybd coloured by chain, top view.
Source organisms:
Primary publication:
Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence.
Sharma R, Gangwar SP, Saxena AK
Acta Crystallogr F Struct Biol Commun 74 656-663 (2018)
PMID: 30279318

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-119430 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Transcriptional regulator ERG Chains: A, X
Molecule details ›
Chains: A, X
Length: 97 amino acids
Theoretical weight: 11.65 KDa
Source organism: Homo sapiens
Expression system: Enterobacteria phage L1
UniProt:
  • Canonical: P11308 (Residues: 310-399; Coverage: 19%)
Gene name: ERG
Sequence domains: Ets-domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
DNA (5'-D(P*AP*CP*CP*GP*GP*AP*AP*GP*T)-3') Chains: B, Y
Molecule details ›
Chains: B, Y
Length: 9 nucleotides
Theoretical weight: 2.76 KDa
Source organism: Drosophila saltans
Expression system: Not provided
DNA (5'-D(P*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3') Chains: C, Z
Molecule details ›
Chains: C, Z
Length: 10 nucleotides
Theoretical weight: 3 KDa
Source organism: Drosophila adunca
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: C2221
Unit cell:
a: 39.279Å b: 233.871Å c: 80.524Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.204 0.282
Expression systems:
  • Enterobacteria phage L1
  • Not provided

Quick links

Citations

2 mentions without citation

Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence.
Sharma et al. (2018)
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