5ybc

X-ray diffraction
2.5Å resolution

X-ray structure of native ETS-domain domain of Ergp55

Released:
Source organism: Homo sapiens
Primary publication:
Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence.
Acta Crystallogr F Struct Biol Commun 74 656-663 (2018)
PMID: 30279318

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional regulator ERG Chains: A, C
Molecule details ›
Chains: A, C
Length: 92 amino acids
Theoretical weight: 10.94 KDa
Source organism: Homo sapiens
Expression system: Enterobacteria phage L1
UniProt:
  • Canonical: P11308 (Residues: 317-408; Coverage: 19%)
Gene name: ERG
Sequence domains: Ets-domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P41212
Unit cell:
a: 64.565Å b: 64.565Å c: 128.305Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.222 0.257
Expression system: Enterobacteria phage L1