5y41

X-ray diffraction
2.05Å resolution

Crystal Structure of LIGAND-BOUND NURR1-LBD

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear receptor subfamily 4 group A member 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 271 amino acids
Theoretical weight: 30.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P43354 (Residues: 328-598; Coverage: 45%)
Gene names: NOT, NR4A2, NURR1, TINUR
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P21212
Unit cell:
a: 88.52Å b: 131.46Å c: 47.13Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.206 0.253
Expression system: Escherichia coli