X-ray diffraction
2.21Å resolution

Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with a berberine derivative (SYSU-00679)

Source organism: Ostrinia furnacalis
Entry authors: Duan YW, Liu T, Zhou Y, Tang JY, Li M, Yang Q

Function and Biology Details

Reaction catalysed:
Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Chitooligosaccharidolytic beta-N-acetylglucosaminidase Chain: A
Molecule details ›
Chain: A
Length: 578 amino acids
Theoretical weight: 66.38 KDa
Source organism: Ostrinia furnacalis
Expression system: Komagataella phaffii GS115
  • Canonical: Q06GJ0 (Residues: 23-594; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P3221
Unit cell:
a: 107.983Å b: 107.983Å c: 175.529Å
α: 90° β: 90° γ: 120°
R R work R free
0.172 0.171 0.192
Expression system: Komagataella phaffii GS115