X-ray diffraction
2.42Å resolution

Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with berberine

Source organism: Ostrinia furnacalis

Function and Biology Details

Reaction catalysed:
Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Chitooligosaccharidolytic beta-N-acetylglucosaminidase Chain: A
Molecule details ›
Chain: A
Length: 578 amino acids
Theoretical weight: 66.38 KDa
Source organism: Ostrinia furnacalis
Expression system: Komagataella phaffii GS115
  • Canonical: Q06GJ0 (Residues: 23-594; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P3221
Unit cell:
a: 107.821Å b: 107.821Å c: 175.098Å
α: 90° β: 90° γ: 120°
R R work R free
0.18 0.179 0.203
Expression system: Komagataella phaffii GS115