X-ray diffraction
3Å resolution

Crystal structure of the protein kinase CK2 catalytic domain from Plasmodium falciparum bound to ATP


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Protein kinase domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 332 amino acids
Theoretical weight: 39.7 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
  • Canonical: Q8IIR9 (Residues: 12-335; Coverage: 97%)
Gene name: PF3D7_1108400
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 88.41Å b: 123.55Å c: 125.65Å
α: 90° β: 90° γ: 90°
R R work R free
0.174 0.172 0.216
Expression system: Escherichia coli