5xtk

X-ray diffraction
1.74Å resolution

Crystal structure of Xanthine-guanine phosphoribosyltransferase from Yersinia pestis

Released:
Source organism: Yersinia pestis
Entry authors: Pavithra GC, Ramagopal UA

Function and Biology Details

Reaction catalysed:
XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Xanthine-guanine phosphoribosyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 152 amino acids
Theoretical weight: 16.99 KDa
Source organism: Yersinia pestis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8ZC05 (Residues: 1-152; Coverage: 100%)
Gene names: YPO3225, YP_0708, gpt, y0963
Sequence domains: Phosphoribosyl transferase domain
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P4322
Unit cell:
a: 66.557Å b: 66.557Å c: 165.379Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.166 0.197
Expression system: Escherichia coli BL21(DE3)