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Cryo-EM structure of human respiratory supercomplex I1III2IV1

Electron Microscopy
3.9Å resolution
PDB entry 5xth coloured by chain, front view.
PDB entry 5xth coloured by chain, side view.
PDB entry 5xth coloured by chain, top view.
Source organisms:
Assembly composition:
hetero 80-mer (preferred)
Entry contents: 68 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero 80-mer
PDBe Complex ID: PDB-CPX-110813

Macromolecules

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Chain: A
Length: 431 amino acids
Theoretical weight: 47.32 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P49821 (Residues: 27-457; Coverage: 93%)
Gene names: NDUFV1, UQOR1
Pfam:
InterPro:
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
Chain: B
Length: 176 amino acids
Theoretical weight: 20.31 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O00217 (Residues: 35-210; Coverage: 84%)
Gene name: NDUFS8
Pfam: 4Fe-4S dicluster domain
InterPro:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
Chain: C
Length: 156 amino acids
Theoretical weight: 17.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O75251 (Residues: 58-213; Coverage: 73%)
Gene name: NDUFS7
Pfam: NADH ubiquinone oxidoreductase, 20 Kd subunit
InterPro:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
Chain: E
Length: 113 amino acids
Theoretical weight: 13.76 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P56556 (Residues: 16-128; Coverage: 88%)
Gene names: LYRM6, NADHB14, NDUFA6
Pfam: Complex1_LYR-like
InterPro:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
Chain: F
Length: 83 amino acids
Theoretical weight: 9.54 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O43678 (Residues: 14-96; Coverage: 84%)
Gene name: NDUFA2
Pfam: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
InterPro:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 in PDB entry 5xth, assembly 1, top view.
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Acyl carrier protein, mitochondrial
Chains: G, X
Length: 85 amino acids
Theoretical weight: 9.85 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O14561 (Residues: 72-156; Coverage: 55%)
Gene name: NDUFAB1
Pfam: Phosphopantetheine attachment site
InterPro:
Acyl carrier protein, mitochondrial in PDB entry 5xth, assembly 1, front view.
Acyl carrier protein, mitochondrial in PDB entry 5xth, assembly 1, side view.
Acyl carrier protein, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
Chain: H
Length: 112 amino acids
Theoretical weight: 13.12 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q16718 (Residues: 5-116; Coverage: 97%)
Gene name: NDUFA5
Pfam: ETC complex I subunit conserved region
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Chain: I
Length: 110 amino acids
Theoretical weight: 12.28 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O95182 (Residues: 4-113; Coverage: 97%)
Gene name: NDUFA7
Pfam: NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
Chain: J
Length: 337 amino acids
Theoretical weight: 38.39 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q16795 (Residues: 40-376; Coverage: 89%)
Gene names: NDUFA9, NDUFS2L
Pfam: NAD dependent epimerase/dehydratase family
InterPro:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
Chain: K
Length: 33 amino acids
Theoretical weight: 3.9 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P56181 (Residues: 74-106; Coverage: 31%)
Gene name: NDUFV3
Pfam: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
InterPro: NADH-ubiquinone oxidoreductase flavoprotein 3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
Chain: L
Length: 118 amino acids
Theoretical weight: 13.72 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O43181 (Residues: 58-175; Coverage: 67%)
Gene name: NDUFS4
Pfam: NADH dehydrogenase ubiquinone Fe-S protein 4
InterPro:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
Chain: M
Length: 687 amino acids
Theoretical weight: 75.47 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P28331 (Residues: 30-716; Coverage: 95%)
Gene name: NDUFS1
Pfam:
InterPro:
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
Chain: N
Length: 143 amino acids
Theoretical weight: 16.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9UI09 (Residues: 2-144; Coverage: 99%)
Gene names: DAP13, NDUFA12
Pfam: NADH ubiquinone oxidoreductase subunit NDUFA12
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
Chain: O
Length: 212 amino acids
Theoretical weight: 23.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P19404 (Residues: 36-247; Coverage: 85%)
Gene name: NDUFV2
Pfam: Thioredoxin-like [2Fe-2S] ferredoxin
InterPro:
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
Chain: P
Length: 208 amino acids
Theoretical weight: 24.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O75489 (Residues: 43-250; Coverage: 79%)
Gene name: NDUFS3
Pfam: Respiratory-chain NADH dehydrogenase, 30 Kd subunit
InterPro:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
Chain: Q
Length: 430 amino acids
Theoretical weight: 49.24 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O75306 (Residues: 34-463; Coverage: 93%)
Gene name: NDUFS2
Pfam: Respiratory-chain NADH dehydrogenase, 49 Kd subunit
InterPro:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
Chain: S
Length: 70 amino acids
Theoretical weight: 8.08 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O15239 (Residues: 1-70; Coverage: 100%)
Gene name: NDUFA1
Pfam: NADH-ubiquinone oxidoreductase MWFE subunit
InterPro: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
Chain: T
Length: 95 amino acids
Theoretical weight: 10.58 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O75380 (Residues: 29-123; Coverage: 77%)
Gene name: NDUFS6
Pfam: Zinc-finger domain
InterPro:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
Chain: U
Length: 83 amino acids
Theoretical weight: 9.16 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O95167 (Residues: 2-84; Coverage: 99%)
Gene name: NDUFA3
Pfam: NADH dehydrogenase 1 alpha subcomplex subunit 3
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
Chain: V
Length: 140 amino acids
Theoretical weight: 14.74 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q86Y39 (Residues: 2-141; Coverage: 99%)
Gene name: NDUFA11
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
Chain: W
Length: 138 amino acids
Theoretical weight: 16.13 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9P0J0 (Residues: 7-144; Coverage: 96%)
Gene names: CDA016, CGI-39, GRIM19, NDUFA13
Pfam: GRIM-19 protein
InterPro: GRIM-19
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
Chain: Y
Length: 59 amino acids
Theoretical weight: 7.47 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O95178 (Residues: 39-97; Coverage: 56%)
Gene name: NDUFB2
Pfam: NADH dehydrogenase 1 beta subcomplex subunit 2
InterPro: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, animal type
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
Chain: Z
Length: 80 amino acids
Theoretical weight: 9.26 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O43676 (Residues: 10-89; Coverage: 82%)
Gene name: NDUFB3
Pfam: NADH-ubiquinone oxidoreductase B12 subunit family
InterPro: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
Chain: a
Length: 138 amino acids
Theoretical weight: 16.57 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O43674 (Residues: 52-189; Coverage: 73%)
Gene name: NDUFB5
Pfam: NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
InterPro: NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6
Chain: b
Length: 124 amino acids
Theoretical weight: 15.01 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O95139 (Residues: 3-126; Coverage: 97%)
Gene name: NDUFB6
Pfam: NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit
InterPro: NADH dehydrogenase 1, beta subcomplex, subunit 6
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
Chain: c
Length: 153 amino acids
Theoretical weight: 18.27 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O95169 (Residues: 34-186; Coverage: 82%)
Gene name: NDUFB8
Pfam: NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
InterPro:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
Chain: d
Length: 171 amino acids
Theoretical weight: 20.72 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O96000 (Residues: 1-171; Coverage: 99%)
Gene name: NDUFB10
Pfam: NADH-ubiquinone oxidoreductase subunit 10
InterPro:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
Chain: e
Length: 97 amino acids
Theoretical weight: 11.49 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NX14 (Residues: 54-150; Coverage: 63%)
Gene names: NDUFB11, UNQ111/PRO1064
Pfam: ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
InterPro: NADH:ubiquinone oxidoreductase, ESSS subunit
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
Chain: f
Length: 47 amino acids
Theoretical weight: 5.7 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O43677 (Residues: 28-74; Coverage: 62%)
Gene name: NDUFC1
Pfam: NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
InterPro: NADH-ubiquinone oxidoreductase 1 subunit C1
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 subunit C2
Chain: g
Length: 119 amino acids
Theoretical weight: 14.21 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O95298 (Residues: 1-119; Coverage: 100%)
Gene names: HLC1, NDUFC2
Pfam: NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2)
InterPro: NADH dehydrogenase [ubiquinone] 1 subunit C2, NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 subunit C2 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 subunit C2 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
Chain: h
Length: 104 amino acids
Theoretical weight: 12.31 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O43920 (Residues: 2-105; Coverage: 98%)
Gene name: NDUFS5
Pfam: NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
InterPro: NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 in PDB entry 5xth, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 2
Chain: i
Length: 347 amino acids
Theoretical weight: 39.01 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P03891 (Residues: 1-347; Coverage: 100%)
Gene names: MT-ND2, MTND2, NADH2, ND2
Pfam:
InterPro:
NADH-ubiquinone oxidoreductase chain 2 in PDB entry 5xth, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 2 in PDB entry 5xth, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 2 in PDB entry 5xth, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 3
Chain: j
Length: 115 amino acids
Theoretical weight: 13.15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: B9EE38 (Residues: 1-115; Coverage: 99%)
Gene name: NADH3
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
InterPro:
NADH-ubiquinone oxidoreductase chain 3 in PDB entry 5xth, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 3 in PDB entry 5xth, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 3 in PDB entry 5xth, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 4L
Chain: k
Length: 97 amino acids
Theoretical weight: 10.7 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: V9JN72 (Residues: 1-97; Coverage: 99%)
Gene name: ND4L
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
InterPro:
NADH-ubiquinone oxidoreductase chain 4L in PDB entry 5xth, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 4L in PDB entry 5xth, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 4L in PDB entry 5xth, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 5
Chain: l
Length: 603 amino acids
Theoretical weight: 67.1 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P03915 (Residues: 1-603; Coverage: 100%)
Gene names: MT-ND5, MTND5, NADH5, ND5
Pfam:
InterPro:
NADH-ubiquinone oxidoreductase chain 5 in PDB entry 5xth, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 5 in PDB entry 5xth, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 5 in PDB entry 5xth, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 6
Chain: m
Length: 174 amino acids
Theoretical weight: 18.66 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8HAX7 (Residues: 1-174; Coverage: 100%)
Gene name: ND6
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase chain 6
InterPro: NADH:ubiquinone/plastoquinone oxidoreductase, chain 6
NADH-ubiquinone oxidoreductase chain 6 in PDB entry 5xth, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 6 in PDB entry 5xth, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 6 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
Chain: n
Length: 56 amino acids
Theoretical weight: 6.74 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O75438 (Residues: 3-58; Coverage: 97%)
Gene name: NDUFB1
Pfam: MNLL subunit
InterPro: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1, NDUB1
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
Chain: o
Length: 128 amino acids
Theoretical weight: 15.1 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O95168 (Residues: 2-129; Coverage: 99%)
Gene name: NDUFB4
Pfam: NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
InterPro: NADH:ubiquinone oxidoreductase, subunit NDUFB4
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
Chain: p
Length: 172 amino acids
Theoretical weight: 21.19 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y6M9 (Residues: 8-179; Coverage: 96%)
Gene names: LYRM3, NDUFB9, UQOR22
Pfam: Complex 1 protein (LYR family)
InterPro:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 in PDB entry 5xth, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 4
Chain: r
Length: 459 amino acids
Theoretical weight: 51.69 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P03905 (Residues: 1-459; Coverage: 100%)
Gene names: MT-ND4, MTND4, NADH4, ND4
Pfam:
InterPro:
NADH-ubiquinone oxidoreductase chain 4 in PDB entry 5xth, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 4 in PDB entry 5xth, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 4 in PDB entry 5xth, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 1
Chain: s
Length: 318 amino acids
Theoretical weight: 35.62 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: H9PGF0 (Residues: 1-318; Coverage: 100%)
Gene name: ND1
Pfam: NADH dehydrogenase
InterPro:
NADH-ubiquinone oxidoreductase chain 1 in PDB entry 5xth, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 1 in PDB entry 5xth, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 1 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
Chain: u
Length: 169 amino acids
Theoretical weight: 19.85 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P51970 (Residues: 4-172; Coverage: 98%)
Gene name: NDUFA8
Pfam: CHCH domain
InterPro:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
Chain: v
Length: 122 amino acids
Theoretical weight: 15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P17568 (Residues: 3-124; Coverage: 89%)
Gene name: NDUFB7
Pfam: NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)
InterPro: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7, NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 in PDB entry 5xth, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
Chain: w
Length: 320 amino acids
Theoretical weight: 37.2 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O95299 (Residues: 36-355; Coverage: 90%)
Gene name: NDUFA10
Pfam: Deoxynucleoside kinase
InterPro:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial in PDB entry 5xth, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial in PDB entry 5xth, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 1
Chain: x
Length: 514 amino acids
Theoretical weight: 57.07 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00396 (Residues: 1-514; Coverage: 100%)
Gene names: COI, COXI, MT-CO1, MTCO1
Pfam: Cytochrome C and Quinol oxidase polypeptide I
InterPro:
Cytochrome c oxidase subunit 1 in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 1 in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 1 in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 2
Chain: y
Length: 227 amino acids
Theoretical weight: 26.04 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P68530 (Residues: 1-227; Coverage: 100%)
Gene names: COII, COX2, COXII, MT-CO2, MTCO2
Pfam:
InterPro:
Cytochrome c oxidase subunit 2 in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 2 in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 2 in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 3
Chain: z
Length: 261 amino acids
Theoretical weight: 29.96 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00415 (Residues: 1-261; Coverage: 100%)
Gene names: COIII, COXIII, MT-CO3, MTCO3
Pfam: Cytochrome c oxidase subunit III
InterPro:
Cytochrome c oxidase subunit 3 in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 3 in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 3 in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Chain: 0
Length: 144 amino acids
Theoretical weight: 16.91 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00423 (Residues: 26-169; Coverage: 85%)
Gene names: COX4, COX4I1
Pfam: Cytochrome c oxidase subunit IV
InterPro:
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 5A, mitochondrial
Chain: 1
Length: 109 amino acids
Theoretical weight: 12.45 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00426 (Residues: 44-152; Coverage: 72%)
Gene name: COX5A
Pfam: Cytochrome c oxidase subunit Va
InterPro:
Cytochrome c oxidase subunit 5A, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 5A, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 5A, mitochondrial in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 5B, mitochondrial
Chain: 2
Length: 98 amino acids
Theoretical weight: 10.68 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00428 (Residues: 32-129; Coverage: 76%)
Gene name: COX5B
Pfam: Cytochrome c oxidase subunit Vb
InterPro:
Cytochrome c oxidase subunit 5B, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 5B, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 5B, mitochondrial in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 6A2, mitochondrial
Chain: 3
Length: 84 amino acids
Theoretical weight: 9.45 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P07471 (Residues: 13-96; Coverage: 87%)
Gene names: COX6A, COX6A2
Pfam: Cytochrome c oxidase subunit VIa
InterPro:
Cytochrome c oxidase subunit 6A2, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 6A2, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 6A2, mitochondrial in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 6B1
Chain: 4
Length: 75 amino acids
Theoretical weight: 8.93 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00429 (Residues: 12-86; Coverage: 87%)
Gene names: COX6B, COX6B1
Pfam: Cytochrome oxidase c subunit VIb
InterPro:
Cytochrome c oxidase subunit 6B1 in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 6B1 in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 6B1 in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 6C
Chain: 5
Length: 73 amino acids
Theoretical weight: 8.49 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P04038 (Residues: 2-74; Coverage: 99%)
Gene name: COX6C
Pfam: Cytochrome c oxidase subunit VIc
InterPro:
Cytochrome c oxidase subunit 6C in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 6C in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 6C in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 7A1, mitochondrial
Chain: 6
Length: 56 amino acids
Theoretical weight: 6.29 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P07470 (Residues: 22-77; Coverage: 70%)
Gene names: COX7A, COX7A1, COX7AH
Pfam: Cytochrome c oxidase subunit VII
InterPro:
Cytochrome c oxidase subunit 7A1, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 7A1, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 7A1, mitochondrial in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 7B, mitochondrial
Chain: 7
Length: 49 amino acids
Theoretical weight: 5.44 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P13183 (Residues: 30-78; Coverage: 61%)
Gene name: COX7B
Pfam: Cytochrome C oxidase chain VIIB
InterPro:
Cytochrome c oxidase subunit 7B, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 7B, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 7B, mitochondrial in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 7C, mitochondrial
Chain: 8
Length: 47 amino acids
Theoretical weight: 5.45 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00430 (Residues: 17-63; Coverage: 75%)
Gene names: COX7C, COX7CP1
Pfam: Cytochrome c oxidase subunit VIIc
InterPro:
Cytochrome c oxidase subunit 7C, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 7C, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 7C, mitochondrial in PDB entry 5xth, assembly 1, top view.
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Cytochrome c oxidase subunit 8B, mitochondrial
Chain: 9
Length: 43 amino acids
Theoretical weight: 4.74 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P10175 (Residues: 25-67; Coverage: 61%)
Gene names: COX8B, COX8H
Pfam: Cytochrome oxidase c subunit VIII
InterPro:
Cytochrome c oxidase subunit 8B, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome c oxidase subunit 8B, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome c oxidase subunit 8B, mitochondrial in PDB entry 5xth, assembly 1, top view.
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Cytochrome b-c1 complex subunit 8
Chains: AA, AN
Length: 81 amino acids
Theoretical weight: 9.79 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O14949 (Residues: 2-82; Coverage: 99%)
Gene name: UQCRQ
Pfam: UcrQ family
InterPro:
Cytochrome b-c1 complex subunit 8 in PDB entry 5xth, assembly 1, front view.
Cytochrome b-c1 complex subunit 8 in PDB entry 5xth, assembly 1, side view.
Cytochrome b-c1 complex subunit 8 in PDB entry 5xth, assembly 1, top view.
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Cytochrome b-c1 complex subunit 9
Chains: AB, AO
Length: 57 amino acids
Theoretical weight: 5.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P47985 (Residues: 1-57; Coverage: 21%)
Gene name: UQCRFS1
Pfam: Ubiquinol-cytochrome c reductase 8 kDa, N-terminal
InterPro:
Cytochrome b-c1 complex subunit 9 in PDB entry 5xth, assembly 1, front view.
Cytochrome b-c1 complex subunit 9 in PDB entry 5xth, assembly 1, side view.
Cytochrome b-c1 complex subunit 9 in PDB entry 5xth, assembly 1, top view.
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Cytochrome b-c1 complex subunit Rieske, mitochondrial
Chains: AC, AP
Length: 196 amino acids
Theoretical weight: 21.65 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P47985 (Residues: 79-274; Coverage: 72%)
Gene name: UQCRFS1
Pfam:
InterPro:
Cytochrome b-c1 complex subunit Rieske, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome b-c1 complex subunit Rieske, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome b-c1 complex subunit Rieske, mitochondrial in PDB entry 5xth, assembly 1, top view.
Molecule details ›

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Cytochrome b-c1 complex subunit 9
Chains: AD, AQ
Length: 62 amino acids
Theoretical weight: 7.19 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9UDW1 (Residues: 2-63; Coverage: 98%)
Gene names: HSPC119, UCRC, UQCR10
Pfam: Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like
InterPro:
Cytochrome b-c1 complex subunit 9 in PDB entry 5xth, assembly 1, front view.
Cytochrome b-c1 complex subunit 9 in PDB entry 5xth, assembly 1, side view.
Cytochrome b-c1 complex subunit 9 in PDB entry 5xth, assembly 1, top view.
Molecule details ›

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Cytochrome b-c1 complex subunit 6, mitochondrial
Chains: AE, AR
Length: 74 amino acids
Theoretical weight: 8.86 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P07919 (Residues: 18-91; Coverage: 81%)
Gene name: UQCRH
Pfam: Ubiquinol-cytochrome C reductase hinge protein
InterPro:
Cytochrome b-c1 complex subunit 6, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome b-c1 complex subunit 6, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome b-c1 complex subunit 6, mitochondrial in PDB entry 5xth, assembly 1, top view.
Molecule details ›

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Cytochrome b-c1 complex subunit 7
Chains: AF, AS
Length: 106 amino acids
Theoretical weight: 13.04 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P14927 (Residues: 6-111; Coverage: 96%)
Gene names: UQBP, UQCRB
Pfam: Ubiquinol-cytochrome C reductase complex 14kD subunit
InterPro:
Cytochrome b-c1 complex subunit 7 in PDB entry 5xth, assembly 1, front view.
Cytochrome b-c1 complex subunit 7 in PDB entry 5xth, assembly 1, side view.
Cytochrome b-c1 complex subunit 7 in PDB entry 5xth, assembly 1, top view.
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Cytochrome b-c1 complex subunit 10
Chains: AG, AT
Length: 51 amino acids
Theoretical weight: 5.96 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O14957 (Residues: 2-52; Coverage: 91%)
Gene names: UQCR, UQCR11
Pfam: Ubiquinol-cytochrome C reductase complex, 6.4kD protein
InterPro:
Cytochrome b-c1 complex subunit 10 in PDB entry 5xth, assembly 1, front view.
Cytochrome b-c1 complex subunit 10 in PDB entry 5xth, assembly 1, side view.
Cytochrome b-c1 complex subunit 10 in PDB entry 5xth, assembly 1, top view.
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Cytochrome c1, heme protein, mitochondrial
Chains: AH, AU
Length: 241 amino acids
Theoretical weight: 27.39 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P08574 (Residues: 85-325; Coverage: 74%)
Gene name: CYC1
Pfam: Cytochrome C1 family
InterPro:
Cytochrome c1, heme protein, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome c1, heme protein, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome c1, heme protein, mitochondrial in PDB entry 5xth, assembly 1, top view.
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Cytochrome b
Chains: AJ, AV
Length: 378 amino acids
Theoretical weight: 42.54 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P00156 (Residues: 2-379; Coverage: 100%)
Gene names: COB, CYTB, MT-CYB, MTCYB
Pfam:
InterPro:
Cytochrome b in PDB entry 5xth, assembly 1, front view.
Cytochrome b in PDB entry 5xth, assembly 1, side view.
Cytochrome b in PDB entry 5xth, assembly 1, top view.
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Cytochrome b-c1 complex subunit 2, mitochondrial
Chains: AK, AW
Length: 419 amino acids
Theoretical weight: 44.95 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P22695 (Residues: 35-453; Coverage: 93%)
Gene name: UQCRC2
Pfam:
InterPro:
Cytochrome b-c1 complex subunit 2, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome b-c1 complex subunit 2, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome b-c1 complex subunit 2, mitochondrial in PDB entry 5xth, assembly 1, top view.
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Cytochrome b-c1 complex subunit 1, mitochondrial
Chains: AL, AY
Length: 446 amino acids
Theoretical weight: 49.18 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P31930 (Residues: 35-480; Coverage: 93%)
Gene name: UQCRC1
Pfam:
InterPro:
Cytochrome b-c1 complex subunit 1, mitochondrial in PDB entry 5xth, assembly 1, front view.
Cytochrome b-c1 complex subunit 1, mitochondrial in PDB entry 5xth, assembly 1, side view.
Cytochrome b-c1 complex subunit 1, mitochondrial in PDB entry 5xth, assembly 1, top view.
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