Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 180-mer (preferred)
Assembly name:
Genome polyprotein (preferred)
PDBe Complex ID:
PDB-CPX-102317 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Genome polyprotein
Molecule details ›
Chain: A
Length: 305 amino acids
Theoretical weight: 33.47 KDa
Source organism: Coxsackievirus A6
UniProt:
Structure domains: Jelly Rolls
Length: 305 amino acids
Theoretical weight: 33.47 KDa
Source organism: Coxsackievirus A6
UniProt:
- Canonical:
A0A0K2BNC7 (Residues: 566-870; Coverage: 14%)
Structure domains: Jelly Rolls
Genome polyprotein
Molecule details ›
Chain: B
Length: 256 amino acids
Theoretical weight: 28.1 KDa
Source organism: Coxsackievirus A6
UniProt:
Structure domains: Jelly Rolls
Length: 256 amino acids
Theoretical weight: 28.1 KDa
Source organism: Coxsackievirus A6
UniProt:
- Canonical: A0A0K2BNC7 (Residues: 70-325; Coverage: 12%)
Structure domains: Jelly Rolls
Genome polyprotein
Molecule details ›
Chain: C
Length: 240 amino acids
Theoretical weight: 26.27 KDa
Source organism: Coxsackievirus A6
UniProt:
Structure domains: Jelly Rolls
Length: 240 amino acids
Theoretical weight: 26.27 KDa
Source organism: Coxsackievirus A6
UniProt:
- Canonical: A0A0K2BNC7 (Residues: 326-565; Coverage: 11%)
Structure domains: Jelly Rolls
