X-ray diffraction
2.38Å resolution

Crystal structure of Mycobacterium tuberculosis methionyl-tRNA synthetase bound by methionyl-adenylate (Met-AMP)


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Methionine--tRNA ligase Chain: C
Molecule details ›
Chain: C
Length: 529 amino acids
Theoretical weight: 59.42 KDa
Source organism: Mycobacterium tuberculosis H37Ra
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
  • Canonical: A5U150 (Residues: 1-519; Coverage: 100%)
Gene names: MRA_1016, metG
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: R3
Unit cell:
a: 198.017Å b: 198.017Å c: 39.161Å
α: 90° β: 90° γ: 120°
R R work R free
0.204 0.201 0.251
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'