5xd4

X-ray diffraction
1.47Å resolution

Crystal structure of Mycobacterium smegmatis MutT1 in complex with ATP (II)

Released:
Entry authors: Arif SM, Varshney U, Vijayan M

Function and Biology Details

Reactions catalysed:
8-oxo-GDP + H(2)O = 8-oxo-GMP + phosphate
8-oxo-GTP + H(2)O = 8-oxo-GDP + phosphate
P(1),P(4)-bis(5'-adenosyl)tetraphosphate + H(2)O = ATP + AMP
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
8-oxo-(d)GTP phosphatase Chain: A
Molecule details ›
Chain: A
Length: 342 amino acids
Theoretical weight: 38.15 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli
UniProt:
  • Canonical: A0QUZ2 (Residues: 1-322; Coverage: 100%)
Gene names: MSMEG_2390, MSMEI_2330, mutT1
Sequence domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 41.95Å b: 84.18Å c: 43.42Å
α: 90° β: 93.37° γ: 90°
R-values:
R R work R free
0.125 0.123 0.16
Expression system: Escherichia coli