5xbm

X-ray diffraction
3.5Å resolution

Structure of SCARB2-JL2 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (6 distinct):
light chain of JL2 Chains: A, D
Molecule details ›
Chains: A, D
Length: 213 amino acids
Theoretical weight: 23.54 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
heavy chain of JL2 Chains: B, E
Molecule details ›
Chains: B, E
Length: 222 amino acids
Theoretical weight: 23.99 KDa
Source organism: Mus musculus
Lysosome membrane protein 2 Chains: C, F
Molecule details ›
Chains: C, F
Length: 394 amino acids
Theoretical weight: 45.22 KDa
Source organism: Homo sapiens
Expression system: Baculovirus expression vector pFastBac1-HM
UniProt:
  • Canonical: Q14108 (Residues: 37-430; Coverage: 82%)
Gene names: CD36L2, LIMP2, LIMPII, SCARB2
Sequence domains: CD36 family

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: C2
Unit cell:
a: 199.863Å b: 75.646Å c: 164.305Å
α: 90° β: 100.11° γ: 90°
R-values:
R R work R free
0.241 0.238 0.293
Expression system: Baculovirus expression vector pFastBac1-HM