› 5x9w

X-ray diffraction
3.3Å resolution

Mismatch Repair Protein

Released:
DOI: 10.2210/pdb5x9w/pdb
PDB entry 5x9w coloured by chain, front view.
PDB entry 5x9w coloured by chain, side view.
PDB entry 5x9w coloured by chain, top view.
Source organism: Neisseria gonorrhoeae FA 1090
Primary publication:
Mechanism of formation of a toroid around DNA by the mismatch sensor protein.
Nirwal S, Kulkarni DS, Sharma A, Rao DN, Nair DT
Nucleic Acids Res 46 256-266 (2018)
PMID: 29182773

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177053 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA mismatch repair protein MutS Chains: A, B
Molecule details ›
Chains: A, B
Length: 816 amino acids
Theoretical weight: 89.9 KDa
Source organism: Neisseria gonorrhoeae FA 1090
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5F5J4 (Residues: 1-814; Coverage: 94%)
Gene names: NGO1930, mutS
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ANP 2 x ANP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Unit cell:
a: 89.51Å b: 102.07Å c: 235.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.221 0.273
Expression system: Escherichia coli

Quick links

Citations

5 citation in other articles

The full-length structure of Thermus scotoductus OLD defines the ATP hydrolysis properties and catalytic mechanism of Class 1 OLD family nucleases.
Schiltz et al. (2020)
4 more

3 mentions without citation

Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue.
Cerullo et al. (2022)
2 more