› 5x7f

X-ray diffraction
2Å resolution

Structure of a O-methyltransferase from Mycobacterium tuberculosis at 2.0 resolution

Released:
DOI: 10.2210/pdb5x7f/pdb
PDB entry 5x7f coloured by chain, front view.
PDB entry 5x7f coloured by chain, side view.
PDB entry 5x7f coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Entry authors: Yan Q, Jiang D

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161713 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable O-methyltransferase Rv1220c Chain: A
Molecule details ›
Chain: A
Length: 235 amino acids
Theoretical weight: 24.3 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WJZ7 (Residues: 10-224; Coverage: 96%)
Gene name: Rv1220c
Sequence domains: O-methyltransferase
Structure domains: Vaccinia Virus protein VP39

Ligands and Environments

1 bound ligand:
Ligand SAM 1 x SAM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P41212
Unit cell:
a: 57.7Å b: 57.7Å c: 158.163Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.192 0.216
Expression system: Escherichia coli BL21(DE3)

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