5x4g

X-ray diffraction
1.45Å resolution

Crystal structure of Fab fragment of anti-CD147 monoclonal antibody 6H8

Released:
Source organism: Mus musculus
Entry authors: Lin P, Zhang M-Y, Chen X, Ye S, Yu X-L, Zhang R-G, Zhu P, Chen Z-N

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213944 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
6H8 Fab heavy chain Chain: A
Molecule details ›
Chain: A
Length: 241 amino acids
Theoretical weight: 26.33 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins
6H8 Fab light chain Chain: B
Molecule details ›
Chain: B
Length: 234 amino acids
Theoretical weight: 25.91 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Unit cell:
a: 40.104Å b: 100.448Å c: 108.175Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.206 0.226
Expression system: Mus musculus