Solution NMR

Solution NMR Structure of DNA Mismatch Repair Protein MutT (Family Nudix Hydrolase) from Methicillin Resistant Staphylococcus aureus 252

Entry authors: Wahab A, Durreshahwar S, Schwalbe H, Richter C, Choudhary MI

Function and Biology Details

Reaction catalysed:
8-oxo-dGTP + H(2)O = 8-oxo-dGMP + diphosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Nudix hydrolase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 14.91 KDa
Source organism: Staphylococcus aureus subsp. aureus MN8
Expression system: Escherichia coli BL21(DE3)
  • Canonical: A0A0E1XLJ5 (Residues: 1-130; Coverage: 100%)
Gene name: HMPREF0769_10658
Sequence domains: NUDIX domain
Structure domains: Nucleoside Triphosphate Pyrophosphohydrolase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 92%
Refinement method: distance geometry
Chemical shifts: BMR36048  
Expression system: Escherichia coli BL21(DE3)