› 5wkz

X-ray diffraction
1.85Å resolution

VH1-69 germline antibody predicted from CR6261

Released:
DOI: 10.2210/pdb5wkz/pdb
PDB entry 5wkz coloured by chain, front view.
PDB entry 5wkz coloured by chain, side view.
PDB entry 5wkz coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lang S, Lee PS

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-100949 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig-like domain-containing protein; Immunoglobulin heavy variable 1-69D Chain: H
Molecule details ›
Chain: H
Length: 250 amino acids
Theoretical weight: 26.67 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: S6BAM6 (Residues: 20-37, 137-247; Coverage: 43%)
  • Canonical: A0A0B4J2H0 (Residues: 38-117; Coverage: 82%)
Gene name: IGHV1-69D
Sequence domains:
Ig-like domain-containing protein Chain: L
Molecule details ›
Chain: L
Length: 217 amino acids
Theoretical weight: 22.84 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A2NUT2 (Residues: 20-117, 118-235; Coverage: 100%)
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P42212
Unit cell:
a: 84.233Å b: 84.233Å c: 177.544Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.205 0.232
Expression system: Trichoplusia ni

Quick links