EC 3.4.22.69: SARS coronavirus main proteinase
Reaction catalysed:
TSAVLQ-|-SGFRK-NH(2) and SGVTFQ-|-GKFKK the two peptides corresponding to the two self-cleavage sites of the SARS 3C-like proteinase are the two most reactive peptide substrates. The enzyme exhibits a strong preference for substrates containing Gln at P1 position and Leu at P2 position.
Systematic name:
-
Alternative Name(s):
- 3C-like protease
- 3cLpro
- Coronavirus 3C-like protease
- Mpro
- SARS 3C-like protease
- SARS coronavirus 3CL protease
- SARS coronavirus main peptidase
- SARS coronavirus main protease
- SARS-CoV 3CLpro enzyme
- SARS-CoV Mpro
- SARS-CoV main protease
- Severe acute respiratory syndrome coronavirus main protease
EC 3.4.19.12: Ubiquitinyl hydrolase 1
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Systematic name:
-
Alternative Name(s):
- Ubiquitin C-terminal hydrolase
- Ubiquitin carboxyl-terminal hydrolase
- Ubiquitin thiolesterase
- Yeast ubiquitin hydrolase
EC 2.7.7.50: mRNA guanylyltransferase
Reaction catalysed:
GTP + a 5'-diphospho-[mRNA] = diphosphate + a 5'-(5'-triphosphoguanosine)-[mRNA]
Systematic name:
GTP:mRNA guanylyltransferase
Alternative Name(s):
- GTP--RNA guanylyltransferase
- Messenger RNA guanylyltransferase
- Protein lambda-2
- mRNA capping enzyme
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence family
Protein family (Pfam)
InterPro annotationsStructure domains
CATH domains
2.40.10.10
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
Thrombin, subunit H
Homology:
Trypsin-like serine proteases
Occurring in:
