› 5wk2

X-ray diffraction
1.5Å resolution

CRYSTAL STRUCTURE OF ANTI-CCL17 ANTIBODY M116

Released:
DOI: 10.2210/pdb5wk2/pdb
PDB 5wk2 coloured by chain and viewed from the front.
PDB 5wk2 coloured by chain and viewed from the side.
PDB 5wk2 coloured by chain and viewed from the top.
Source organism: Homo sapiens
Entry authors: Teplyakov A, Obmolova G, Gilliland GL

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
M116 LIGHT CHAIN Chain: L
Molecule details ›
Chain: L
Length: 220 amino acids
Theoretical weight: 24.07 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
M116 HEAVY CHAIN Chain: H
Molecule details ›
Chain: H
Length: 230 amino acids
Theoretical weight: 24.71 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand EPE 2 x EPE
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 53.74Å b: 64.92Å c: 73.79Å
α: 90° β: 107.29° γ: 90°
R-values:
R R work R free
0.18 0.18 0.208
Expression system: Homo sapiens

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Citations

1 review citation

Relationship between chemokines and T lymphocytes in the context of respiratory allergies (Review).
Berghi et al. (2020)
2 other articles