X-ray diffraction
1.96Å resolution

Structure of the human D4 Dopamine receptor in complex with Nemonapride


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
D(4) dopamine receptor; Soluble cytochrome b562 Chain: A
Molecule details ›
Chain: A
Length: 422 amino acids
Theoretical weight: 45.31 KDa
Source organisms: Expression system: Insecta
  • Canonical: P0ABE7 (Residues: 24-128; Coverage: 99%)
  • Canonical: P21917 (Residues: 1-228, 335-419; Coverage: 75%)
Gene names: DRD4, cybC
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: C2221
Unit cell:
a: 67.688Å b: 164.047Å c: 84.129Å
α: 90° β: 90° γ: 90°
R R work R free
0.206 0.205 0.236
Expression system: Insecta