PDBe 5wel

Electron Microscopy
4.4Å resolution

GluA2 bound to antagonist ZK and GSG1L in digitonin, state 2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Germ cell-specific gene 1-like protein; Glutamate receptor 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 1057 amino acids
Theoretical weight: 117.47 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
  • Canonical: D3Z7H4 (Residues: 2-204, 205-238; Coverage: 74%)
  • Canonical: P19491 (Residues: 25-847; Coverage: 95%)
  • nullnull
Gene names: Glur2, Gria2, Gsg1l
Sequence domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.4Å
Relevant EMDB volumes: EMD-8820
Expression system: Homo sapiens