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RNA polymerase I Initial Transcribing Complex

Source organism: Saccharomyces cerevisiae S288C
Biochemical function: RNA polymerase I activity
Biological process: nucleolar large rRNA transcription by RNA polymerase I
Cellular component: nucleus

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EC 2.7.7.6: DNA-directed RNA polymerase

Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Systematic name:
Nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed)
Alternative Name(s):
  • C RNA formation factors
  • C ribonucleic acid formation factors
  • DNA-dependent RNA nucleotidyltransferase
  • DNA-dependent RNA polymerase
  • DNA-dependent ribonucleate nucleotidyltransferase
  • Deoxyribonucleic acid-dependent ribonucleic acid polymerase
  • RNA nucleotidyltransferase
  • RNA nucleotidyltransferase (DNA-directed)
  • RNA polymerase
  • RNA polymerase I
  • RNA polymerase II
  • RNA polymerase III
  • RNA transcriptase
  • Ribonucleate nucleotidyltransferase
  • Ribonucleate polymerase
  • Ribonucleic acid nucleotidyltransferase
  • Ribonucleic acid polymerase
  • Ribonucleic acid transcriptase
  • Ribonucleic polymerase
  • Ribonucleic transcriptase
  • Transcriptase

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF01193
Domain description: RNA polymerase Rpb3/Rpb11 dimerisation domain
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC1
  2. DNA-directed RNA polymerases I and III subunit RPAC2
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF01193 (RNA polymerase Rpb3/Rpb11 dimerisation domain) in DNA-directed RNA polymerases I and III subunit RPAC1. Showing 1 copy in chain C.

PF04090
Domain description: RNA polymerase I-specific transcription initiation factor Rrn11
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN11
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF04090 (RNA polymerase I specific initiation factor) in RNA polymerase I-specific transcription initiation factor RRN11. Showing 1 copy in chain Q.

PF20645
Domain description: Rrn7/TAF1B, C-terminal cyclin domain
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN7

PF20644
Domain description: Rrn7/TAF1B, N-terminal cyclin domain
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN7

PF11781
Domain description: Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN7
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF11781 (Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7) in RNA polymerase I-specific transcription initiation factor RRN7. Showing 1 copy in chain P (this domain is out of the observed residue ranges!).

PF20639
Domain description: RRN6, K-rich C-terminal domain
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN6

PF20640
Domain description: Rrn6, helical bundle domain
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN6

PF10214
Domain description: Rrn6, beta-propeller
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN6
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF10214 (RNA polymerase I-specific transcription-initiation factor) in RNA polymerase I-specific transcription initiation factor RRN6. Showing 1 copy in chain O.

PF08208
Domain description: DNA-directed RNA polymerase I subunit RPA34.5
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA34
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF08208 (DNA-directed RNA polymerase I subunit RPA34.5) in DNA-directed RNA polymerase I subunit RPA34. Showing 1 copy in chain N.

PF06870
Domain description: A49-like RNA polymerase I associated factor
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA49
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF06870 (A49-like RNA polymerase I associated factor) in DNA-directed RNA polymerase I subunit RPA49. Showing 1 copy in chain M.

PF03604
Domain description: DNA directed RNA polymerase, 7 kDa subunit
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC4
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF03604 (DNA directed RNA polymerase, 7 kDa subunit) in DNA-directed RNA polymerases I, II, and III subunit RPABC4. Showing 1 copy in chain L.

PF13656
Domain description: RNA polymerase Rpb3/Rpb11 dimerisation domain
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC2
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF13656 (RNA polymerase Rpb3/Rpb11 dimerisation domain) in DNA-directed RNA polymerases I and III subunit RPAC2. Showing 1 copy in chain K.

PF01194
Domain description: RNA polymerases N / 8 kDa subunit
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC5
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF01194 (RNA polymerases N / 8 kDa subunit) in DNA-directed RNA polymerases I, II, and III subunit RPABC5. Showing 1 copy in chain J.

PF01096
Domain description: Transcription factor S-II (TFIIS)
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA12
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF01096 (Transcription factor S-II (TFIIS)) in DNA-directed RNA polymerase I subunit RPA12. Showing 1 copy in chain I (this domain is out of the observed residue ranges!).

PF02150
Domain description: RNA polymerases M/15 Kd subunit
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA12
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF02150 (RNA polymerases M/15 Kd subunit) in DNA-directed RNA polymerase I subunit RPA12. Showing 1 copy in chain I.

PF03870
Domain description: RNA polymerase Rpb8
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC3
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF03870 (RNA polymerase Rpb8) in DNA-directed RNA polymerases I, II, and III subunit RPABC3. Showing 1 copy in chain H.

PF17875
Domain description: RPA43 OB domain in RNA Pol I
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA43
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF17875 (RPA43 OB domain in RNA Pol I) in DNA-directed RNA polymerase I subunit RPA43. Showing 1 copy in chain G.

PF03876
Domain description: SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA43
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF03876 (SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397) in DNA-directed RNA polymerase I subunit RPA43. Showing 1 copy in chain G.

PF01192
Domain description: RNA polymerase Rpb6
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF01192 (RNA polymerase Rpb6) in DNA-directed RNA polymerases I, II, and III subunit RPABC2. Showing 1 copy in chain F.

PF01191
Domain description: RNA polymerase Rpb5, C-terminal domain
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC1
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF01191 (RNA polymerase Rpb5, C-terminal domain) in DNA-directed RNA polymerases I, II, and III subunit RPABC1. Showing 1 copy in chain E.

PF03871
Domain description: RNA polymerase Rpb5, N-terminal domain
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC1
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF03871 (RNA polymerase Rpb5, N-terminal domain) in DNA-directed RNA polymerases I, II, and III subunit RPABC1. Showing 1 copy in chain E.

PF08203
Domain description: Yeast RNA polymerase I subunit RPA14
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA14
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF08203 (Yeast RNA polymerase I subunit RPA14) in DNA-directed RNA polymerase I subunit RPA14. Showing 1 copy in chain D.

PF01000
Domain description: RNA polymerase Rpb3/RpoA insert domain
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC1
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF01000 (RNA polymerase Rpb3/RpoA insert domain) in DNA-directed RNA polymerases I and III subunit RPAC1. Showing 1 copy in chain C.

PF04560
Domain description: RNA polymerase Rpb2, domain 7
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF04560 (RNA polymerase Rpb2, domain 7) in DNA-directed RNA polymerase I subunit RPA135. Showing 1 copy in chain B.

PF00562
Domain description: RNA polymerase Rpb2, domain 6
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF00562 (RNA polymerase Rpb2, domain 6) in DNA-directed RNA polymerase I subunit RPA135. Showing 1 copy in chain B.

PF06883
Domain description: RNA polymerase I, Rpa2 specific domain
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF06883 (RNA polymerase I, Rpa2 specific domain) in DNA-directed RNA polymerase I subunit RPA135. Showing 1 copy in chain B.

PF04565
Domain description: RNA polymerase Rpb2, domain 3
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF04565 (RNA polymerase Rpb2, domain 3) in DNA-directed RNA polymerase I subunit RPA135. Showing 1 copy in chain B.

PF04561
Domain description: RNA polymerase Rpb2, domain 2
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF04561 (RNA polymerase Rpb2, domain 2) in DNA-directed RNA polymerase I subunit RPA135. Showing 1 copy in chain B.

PF04563
Domain description: RNA polymerase beta subunit
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF04563 (RNA polymerase beta subunit) in DNA-directed RNA polymerase I subunit RPA135. Showing 1 copy in chain B.

PF04998
Domain description: RNA polymerase Rpb1, domain 5
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF04998 (RNA polymerase Rpb1, domain 5) in DNA-directed RNA polymerase I subunit RPA190. Showing 1 copy in chain A.

PF05000
Domain description: RNA polymerase Rpb1, domain 4
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF05000 (RNA polymerase Rpb1, domain 4) in DNA-directed RNA polymerase I subunit RPA190. Showing 1 copy in chain A.

PF04983
Domain description: RNA polymerase Rpb1, domain 3
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF04983 (RNA polymerase Rpb1, domain 3) in DNA-directed RNA polymerase I subunit RPA190. Showing 1 copy in chain A.

PF00623
Domain description: RNA polymerase Rpb1, domain 2
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF00623 (RNA polymerase Rpb1, domain 2) in DNA-directed RNA polymerase I subunit RPA190. Showing 1 copy in chain A.

PF04997
Domain description: RNA polymerase Rpb1, domain 1
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
The deposited structure of PDB entry 5w5y contains 1 copy of Pfam domain PF04997 (RNA polymerase Rpb1, domain 1) in DNA-directed RNA polymerase I subunit RPA190. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000268
Domain description: DNA-directed RNA polymerase subunit RPABC5/Rpb10
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC5
IPR001222
Domain description: Zinc finger, TFIIS-type
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA12
IPR036603
Domain description: RNA polymerase, RBP11-like subunit
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC1
  2. DNA-directed RNA polymerases I and III subunit RPAC2
IPR005570
Domain description: DNA-directed RNA polymerases I, II, and III subunit RPABC3
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC3
IPR012340
Domain description: Nucleic acid-binding, OB-fold
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA43
  2. DNA-directed RNA polymerases I, II, and III subunit RPABC3
IPR014381
Domain description: DNA-directed RNA polymerase subunit Rpo5/Rpb5
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC1
IPR019350
Domain description: RNA polymerase I-specific transcription initiation factor RRN6-like
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN6
IPR009668
Domain description: RNA polymerase I associated factor, A49-like
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA49
IPR006591
Domain description: RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC4
IPR012164
Domain description: DNA-directed RNA polymerase subunit/transcription factor S
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA12
IPR001529
Domain description: DNA-directed RNA polymerase, M/15kDa subunit
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA12
IPR006110
Domain description: RNA polymerase, subunit omega/Rpo6/RPB6
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
IPR036161
Domain description: RPB6/omega subunit-like superfamily
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
IPR006111
Domain description: Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
IPR036710
Domain description: RNA polymerase Rpb5, N-terminal domain superfamily
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC1
IPR036643
Domain description: DNA-directed RNA polymerase, insert domain superfamily
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC1
IPR011263
Domain description: DNA-directed RNA polymerase, RpoA/D/Rpb3-type
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC1
IPR015712
Domain description: DNA-directed RNA polymerase, subunit 2
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
IPR007224
Domain description: Transcription initiation factor Rrn11
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN11
IPR016850
Domain description: Transcription initiation factor Rrn11, budding yeast
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN11
IPR033599
Domain description: RNA polymerase I transcription initiation factor TAF1B/Rrn7
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN7
IPR021752
Domain description: Transcription initiation factor Rrn7, Zinc-finger
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN7
IPR016531
Domain description: RNA polymerase I-specific transcription initiation factor Rrn6
Occurring in:
  1. RNA polymerase I-specific transcription initiation factor RRN6
IPR013240
Domain description: DNA-directed RNA polymerase I, subunit RPA34
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA34
IPR029040
Domain description: RNA polymerase subunit RPABC4/transcription elongation factor Spt4
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC4
IPR039747
Domain description: DNA-directed RNA polymerases I, II, and III subunit RPABC4
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC4
IPR008193
Domain description: DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC2
IPR009025
Domain description: DNA-directed RNA polymerase, RBP11-like dimerisation domain
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC2
IPR022905
Domain description: DNA-directed RNA polymerase subunit Rpo11-like
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC2
IPR033898
Domain description: DNA-directed RNA polymerases I and III subunit AC19
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC2
IPR020789
Domain description: RNA polymerases, subunit N, zinc binding site
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC5
IPR023580
Domain description: RNA polymerase subunit RPB10
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC5
IPR034004
Domain description: Pol I subunit A12, C-terminal zinc ribbon
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA12
IPR019761
Domain description: DNA-directed RNA polymerase M, 15kDa subunit, conserved site
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA12
IPR041178
Domain description: RPA43, OB domain
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA43
IPR005576
Domain description: RNA polymerase Rpb7-like , N-terminal
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA43
IPR045113
Domain description: RNA polymerase subunit Rpb7-like
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA43
IPR041901
Domain description: Rpa43, N-terminal ribonucleoprotein (RNP) domain
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA43
IPR036898
Domain description: RNA polymerase Rpb7-like, N-terminal domain superfamily
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA43
IPR020708
Domain description: DNA-directed RNA polymerase, 14-18kDa subunit, conserved site
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
IPR028363
Domain description: DNA-directed RNA polymerase, subunit RPB6
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
IPR020608
Domain description: RNA polymerase, subunit H/Rpb5, conserved site
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC1
IPR000783
Domain description: RNA polymerase, subunit H/Rpb5 C-terminal
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC1
IPR035913
Domain description: RPB5-like RNA polymerase subunit superfamily
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC1
IPR005571
Domain description: RNA polymerase, Rpb5, N-terminal
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC1
IPR013239
Domain description: RNA polymerase I, subunit Rpa14, fungi
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA14
IPR011262
Domain description: DNA-directed RNA polymerase, insert domain
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC1
IPR001514
Domain description: DNA-directed RNA polymerase, 30-40kDa subunit, conserved site
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC1
IPR022842
Domain description: DNA-directed RNA polymerase subunit Rpo3/Rpb3/RPAC1
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC1
IPR033901
Domain description: DNA-directed RNA polymerases I and III subunit AC40
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC1
IPR007641
Domain description: RNA polymerase Rpb2, domain 7
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
IPR007121
Domain description: RNA polymerase, beta subunit, conserved site
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
IPR014724
Domain description: RNA polymerase Rpb2, OB-fold
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
IPR037033
Domain description: DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
IPR007120
Domain description: DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
IPR009674
Domain description: DNA-directed RNA polymerase I subunit RPA2, domain 4
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
IPR007645
Domain description: RNA polymerase Rpb2, domain 3
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
IPR037034
Domain description: RNA polymerase Rpb2, domain 2 superfamily
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
IPR007642
Domain description: RNA polymerase Rpb2, domain 2
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
IPR007644
Domain description: RNA polymerase, beta subunit, protrusion
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
IPR047107
Domain description: DNA-directed RNA pol I, largest subunit, C-terminal domain
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
IPR007081
Domain description: RNA polymerase Rpb1, domain 5
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
IPR007083
Domain description: RNA polymerase Rpb1, domain 4
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
IPR038120
Domain description: RNA polymerase Rpb1, funnel domain superfamily
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
IPR042102
Domain description: RNA polymerase Rpb1, domain 3 superfamily
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
IPR007066
Domain description: RNA polymerase Rpb1, domain 3
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
IPR000722
Domain description: RNA polymerase, alpha subunit
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
IPR006592
Domain description: RNA polymerase, N-terminal
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
IPR045867
Domain description: DNA-directed RNA polymerase, subunit beta-prime
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
IPR015699
Domain description: DNA-directed RNA pol I, largest subunit, N-terminal domain
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
IPR007080
Domain description: RNA polymerase Rpb1, domain 1
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190
IPR044893
Domain description: RNA polymerase Rpb1, clamp domain superfamily
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA190

Structure domains

CATH CATH domains
3.30.1360.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Gyrase A; domain 2
Homology: RNA polymerase, RBP11-like subunit
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC1
  2. DNA-directed RNA polymerases I and III subunit RPAC2
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 3.30.1360.10 (Gyrase A; domain 2) in DNA-directed RNA polymerases I and III subunit RPAC1. Showing 1 copy in chain C.
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 3.30.1360.10 (Gyrase A; domain 2) in DNA-directed RNA polymerases I and III subunit RPAC2. Showing 1 copy in chain K.
2.40.270.10
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6
Homology: DNA-directed RNA polymerase, subunit 2, domain 6
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 2.40.270.10 (Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6) in DNA-directed RNA polymerase I subunit RPA135. Showing 1 copy in chain B.
2.40.50.150
Class: Mainly Beta
Architecture: Beta Barrel
Topology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 2.40.50.150 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in DNA-directed RNA polymerase I subunit RPA135. Showing 1 copy in chain B.
2.20.28.30
Class: Mainly Beta
Architecture: Single Sheet
Topology: Rubrerythrin, domain 2
Homology: RNA polymerase ii, chain L
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC4
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 2.20.28.30 (Rubrerythrin, domain 2) in DNA-directed RNA polymerases I, II, and III subunit RPABC4. Showing 1 copy in chain L.
1.10.10.60
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Homeodomain-like
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC5
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 1.10.10.60 (Arc Repressor Mutant, subunit A) in DNA-directed RNA polymerases I, II, and III subunit RPABC5. Showing 1 copy in chain J.
2.40.50.140
Class: Mainly Beta
Architecture: Beta Barrel
Topology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology: Nucleic acid-binding proteins
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC3
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 2.40.50.140 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in DNA-directed RNA polymerases I, II, and III subunit RPABC3. Showing 1 copy in chain H.
3.90.940.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Eukaryotic RPB6 RNA polymerase subunit
Homology: Eukaryotic RPB6 RNA polymerase subunit
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 3.90.940.10 (Eukaryotic RPB6 RNA polymerase subunit) in DNA-directed RNA polymerases I, II, and III subunit RPABC2. Showing 1 copy in chain F.
3.90.940.20
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Eukaryotic RPB6 RNA polymerase subunit
Homology: RPB5-like RNA polymerase subunit
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC1
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 3.90.940.20 (Eukaryotic RPB6 RNA polymerase subunit) in DNA-directed RNA polymerases I, II, and III subunit RPABC1. Showing 1 copy in chain E.
3.40.1340.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1
Homology: RNA polymerase, Rpb5, N-terminal domain
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC1
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 3.40.1340.10 (Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1) in DNA-directed RNA polymerases I, II, and III subunit RPABC1. Showing 1 copy in chain E.
6.10.250.3390
Class: Special
Architecture: Helix non-globular
Topology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA14
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 6.10.250.3390 (Single alpha-helices involved in coiled-coils or other helix-helix interfaces) in DNA-directed RNA polymerase I subunit RPA14. Showing 1 copy in chain D.
2.170.120.12
Class: Mainly Beta
Architecture: Beta Complex
Topology: RNA Polymerase Alpha Subunit; Chain A, domain 2
Homology: DNA-directed RNA polymerase, insert domain
Occurring in:
  1. DNA-directed RNA polymerases I and III subunit RPAC1
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 2.170.120.12 (RNA Polymerase Alpha Subunit; Chain A, domain 2) in DNA-directed RNA polymerases I and III subunit RPAC1. Showing 1 copy in chain C.
3.90.1800.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: DCoH-like
Homology: RNA polymerase alpha subunit dimerisation domain
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 3.90.1800.10 (DCoH-like) in DNA-directed RNA polymerase I subunit RPA135. Showing 1 copy in chain B.
3.90.1070.20
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Hypothetical Protein Ta0175; Chain: A, domain 2
Homology: Hypothetical Protein Ta0175; Chain: A, domain 2
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 3.90.1070.20 (Hypothetical Protein Ta0175; Chain: A, domain 2) in DNA-directed RNA polymerase I subunit RPA135. Showing 1 copy in chain B.
3.90.1110.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3
Homology: RNA polymerase Rpb2, domain 2
Occurring in:
  1. DNA-directed RNA polymerase I subunit RPA135
The deposited structure of PDB entry 5w5y contains 1 copy of CATH domain 3.90.1110.10 (Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3) in DNA-directed RNA polymerase I subunit RPA135. Showing 1 copy in chain B.

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