PDBe 5w4r

X-ray diffraction
3Å resolution

Structure of RORgt bound to a tertiary alcohol

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear receptor ROR-gamma Chains: A, B
Molecule details ›
Chains: A, B
Length: 217 amino acids
Theoretical weight: 25.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P51449 (Residues: 265-481; Coverage: 42%)
Gene names: NR1F3, RORC, RORG, RZRG

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P61
Unit cell:
a: 97.361Å b: 97.361Å c: 128.218Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.196 0.19 0.245
Expression system: Escherichia coli