X-ray diffraction
1.39Å resolution

SH2B1 SH2 Domain

Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
SH2B adapter protein 1 Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 12.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9NRF2 (Residues: 519-628; Coverage: 15%)
Gene names: KIAA1299, SH2B, SH2B1
Sequence domains: SH2 domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P212121
Unit cell:
a: 29.01Å b: 52.75Å c: 60.73Å
α: 90° β: 90° γ: 90°
R R work R free
0.146 0.144 0.168
Expression system: Escherichia coli BL21(DE3)