5vz3

X-ray diffraction
1.97Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Growth/differentiation factor 15 Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.3 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q99988 (Residues: 197-308; Coverage: 40%)
Gene names: GDF15, MIC1, PDF, PLAB, PTGFB
Sequence domains: Transforming growth factor beta like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C222
Unit cell:
a: 49.964Å b: 123.02Å c: 41.698Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.248
Expression system: Homo sapiens